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Objective To explore the impact of pregnancy knowledge training on contraception and further unplanned pregnancies in outpatient induced abortion patients. Methods Select 114 case of abortion patients in our hospital during March 2015～November 2016, randomly divide them to intervention group (pregnancy knowledge training, 57 cases) and routine group (routine follow-up, 57 cases). Two groups of patients were followed up for 1 year after intervention, compared the mastery of contraceptive knowledge, the incidence of unwanted pregnancies again and satisfaction. Results The intervention group patients health knowledge to master the excellent and good rate was significantly higher than the conventional group (87. 72％ vs. 56. 14％, P＜0. 05). The rate of unexpected pregnancy again was significantly lower in the dry group than in the conventional group (3. 51％ vs. 19. 30％, P＜0. 05). The intervention group patients satisfaction was significantly higher than the conventional group. Conclusion Pregnancy knowledge training in outpatient abortion patients can effectively improve the control of patients with contraceptive knowledge and reduce the incidence of postoperative unwanted pregnancies and improve patient satisfaction.
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OBJECTIVE To observe the efficacy of specific immunotherapy (SIT) with Alutard and NHD in children with allergic rhinitis due to different level of skin prick test (SPT) with dermatophagoides farinae (DF) and dermatophagoides pteronyssinus (DP). METHODS A total of 178 children with persistent allergic rhinitis were included in this study. Their age ranged from 6 to 12 years. They were divided into 3 groups according to level of SPT. Group 1: The level of skin index (SI) of DF is greater than that of DP, Group 2: The level of SI of DF is equal to that of DP and Group 3: The level of SI of DF is less than that of DP. The children in each group were randomly divided into 2 subgroups: Alutard group and NHD group. The children were given SIT with Alutard or NHD for one year. Symptom and medication scores were recorded and analyzed. RESULTS After receiving therapy for 3 months and 6 months, symptom and medication scores of the Group 1 and 2 in the NHD group were lower than those in the Alutard group (P0.05). CONCLUSION The efficacy of SIT with Alutard and NHD is different in children with allergic rhinitis with different levels of SPT due to DF and DP after 3 and 6 months, but is similar after 9 and 12 months. SIT with Alutard and NHD is effective in treating children with allergic rhinitis.
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OBJECTIVE@#To study the mechanism and clinical significance of specific immunotherapy (SIT) on the expression changes of GM-CSF and IL-5 in the tissue samples of recurrent nasal polyps.@*METHOD@#Perennial allergic rhinitis patients with recurrent nasal polyps were randomly divided into 2 groups. The experimental group of 19 patients was treated by SIT and standardized treatment (glucocorticoid nasal spray) , and the control group of 17 patients was only treated by standardized treatment (glucocorticoid nasal spray). We measured the expression levels of GM-CSF and IL-5 in the tissue samples of the nasal polyps by ELISA, and compared the results obtained before treatment with expression levels detected at 6 months and 1 year after the treatment.@*RESULT@#The expression of GM-CSF and IL-5 in the recurrent nasal polyps reduced significantly (P < 0.05) in both groups after 6 months and 1 year post-treatment compared with pre-treatment, and the expression of GM-CSF and IL-5 in the experimental group was much lower than that of the control group.@*CONCLUSION@#SIT decreases the expression of GM-CSF and IL-5 and reduces the inflammatory reaction in the tissue samples of recurrent nasal polyps.
Subject(s)
Humans , Enzyme-Linked Immunosorbent Assay , Granulocyte-Macrophage Colony-Stimulating Factor , Metabolism , Immunotherapy , Inflammation , Drug Therapy , Interleukin-5 , Metabolism , Nasal Mucosa , Pathology , Nasal Polyps , Drug Therapy , Metabolism , Rhinitis, Allergic, Perennial , Drug Therapy , MetabolismABSTRACT
OBJECTIVE@#To evaluate the effect and safety analysis of Allergovit standardized dust mite subcutaneous immunotherapy in patients with allergic rhinitis.@*METHOD@#From Jan 2006 to Jan 2009,425 patients with persistent were treated with Allergovit standardized dust mite allergen in 3 years, which data were retrospectively analyzed. The scores of the rhinoconjunctivitis quality of life were collected per-treatment and three years treatment. VAS (visual analogue scale) of all nasal symptoms and drug use scores were evaluated before treatment and every 6 weeks. The frequency of local and systemic reactions were recorded in the duration of dose escalation and maintenance.@*RESULT@#The Overall QOL were significantly improved after 3 years treatment [pre-treatment: 3.8 (2.9; 4.5); post-treatment: 1.1 (1.0; 2.0), P < 0.01]. VAS of all nasal symptoms and drug used scores decreased dramatically after escalation period [pro-treatment: 23. 7 (20.5; 27.8), 3.9 (3.2; 4.7); post-treatment: 2.1 (1.6; 2.2), 0(0;0), P < 0.01]. Local reaction's rate was 3.15%, the frequency systemic reaction's rate was 0.90%.@*CONCLUSION@#The standardized specific allergen immunotherapy for allergic rhinitis is safe and effective.
Subject(s)
Adolescent , Adult , Animals , Child , Child, Preschool , Female , Humans , Male , Middle Aged , Young Adult , Immunotherapy , Pyroglyphidae , Allergy and Immunology , Quality of Life , Retrospective Studies , Rhinitis, Allergic , Rhinitis, Allergic, Perennial , Therapeutics , Treatment Outcome , Vaccines , Therapeutic UsesABSTRACT
A Neurospora sp was used to ferment organic waste materials such as sugarcane residue powder (bagasse), bran and cassava residue The feed complex enzymes including cellulase, saccharifying enzyme,neutral proteinase and other growth factors were produced The experimental results showed that suitable medium contained sugarcane residue powder 100 g ?bran 600 g, cassava residue 300 g, mixed nitrogen sucrose 20 g per kilogram solid materials and some content of phosphate, the water in medium was twice as weight as the solid materials;the suitable fermentation conditions were that the strain was cultured first for 2 days under 34℃ and then fermented for 2～3 days at 37℃, no light,keeping the watering medium and suppling enough oxygen during fermentation The cellulase (CMC+C1) was 1759mg/g/h, saccharifying enzyme to 3110 mg/g/h, neutral proteinase 297mg/g /h in ferment product On the other hand, light,enough air,lower temperature and less water content in medium were benefit to producing spores